Morin and Morin hydrate (2′,3,4′,5,7-Pentahydroxyflavone, CAS 480-16-0 resp. CAS 654055-01-3) is a bioflavonoid mainly obtained from fruits, stem, and leaves of Moraceae family members' plants. [1] The yellow-beige chemical compound can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic), and from leaves of Psidium guajava (common guava).[2] Other names are: Aurantica, Calico Yellow, Toxylon pomiferum and Bois d'arc.
Morin has been described to have a wide range of pharmacological properties, including anti-inflammatory, antioxidant, free radical scavenging in various diseases like cancer, acute lung injury, liver injury, neuroinflammatory disorders, nephrotoxicity, diabetes, gastritis, mastitis, and myocardial infarction. [1]
Flavonoids such as Morin are the most significant natural antioxidants with intense anti-cancer action under both in-vivo and in-vitro conditions. [3][4]
Since the beginning of industrialization, Morin has been used as the best yellow dye for cotton, wool, and silk. For this purpose, the goods to be dyed were first pretreated with metal salts. Various colors could be achieved by reacting Morin with the metal ions. Morin produces olive-green colors with iron salts, brown-yellow with copper salts, and yellow with lead and tin salts.[5]
In analytical chemistry Morin is used for fluorometric detection experiments for various metal ions like aluminum, beryllium, gallium, indium, scandium, titanium and tin.[5]
From US Patent 5492615 also the use of flavones for the electrolytic deposition of tin layers is known.
Benefits / USP
Despite its large potential and use in industrial scale, Morin is still only available after extraction from a very slow growing tropical tree (mainly Maclura tinctoria or Dyer’s Mulberry), to be found only in the neotropics, making Morin expensive and ecologically unsustainable.
The Morin quality, currently used on the market on a kilogram scale has so far been extracted from tropical timber and is offered in a strongly varying purity between 65% and 85% (m/m).
ORSAtec is addressing the problem of erratic purity thanks to its patented chemical synthesis of Morin (WO2019101353A1).
Thanks to the HPLC controlled purity and high concentration (≥ 95% (m/m)) of ORSAtec´s Morin product it works much better and more predictably than the natural compound.
Packaging and Pricing
ORSAtec´s Morin (CAS 480-16-0, ≥ 95.0 % purity) is available in different pack sizes:
| Amount | Price |
|---|---|
| 1 gram | 35,00 € |
| 5 gram | 50,00 € |
| 25 gram | 225,00 € |
| 1000 gram | 3.850,00 € |
For bulk volumes please request your personal quote.